VHL

About

Location: 3p25.3

Mappings

HGNC: HGNC:12687

Ensembl: ENSG00000134086

NCBI: 7428

Refseq: NM_000551.4

Biomarkers

VHL is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
VHL pathogenic variants Germline Variant 3 6

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Organization(s) Biomarker(s) Cancer type Therapy(ies)
EMA (1) FDA (1) VHL pathogenic variants Renal Cell Carcinoma Belzutifan
EMA (1) FDA (1) VHL pathogenic variants Central Nervous System Hemangioblastoma Belzutifan
EMA (1) FDA (1) VHL pathogenic variants Pancreatic Neuroendocrine Tumor Belzutifan